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Updated: Jun 27, 2026

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
Published on: June 8, 2017
[A histologic study of brain in fatal cerebral malaria]
Fanny Burel-Vandenbos1, Christian Effa'a, Véronique Alunni
1Laboratoire d'anatomie pathologique, hôpital Pasteur, CHU de Nice, 30, avenue de la Voie-Romaine, 06000 Nice, France. burel-vandenbos.f@chu-nice.fr
Abstract:
Plasmodium falciparum infection is an emergency because of the risk of cerebral malaria, that is the most severe complication. Malaria diagnosis is usually made on blood samples of feverish patients coming from endemic area. The pathologist is rarely confronted with malaria lesions. If the occasion arises, the diagnosis of malaria is often already known or suspected and the pathologist has to confirm it. Rarely, malaria is unknown before histological examination and the diagnosis is based on the identification of specific histological features. We report a case of sudden death due to cerebral malaria diagnosed on autopsy findings.

