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Updated: Jun 27, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Off-pump coronary artery bypass grafting in a patient with Werner's syndrome
Satona Tanaka1, Takeshi Miyairi, Shogo Shimada
1Division of Cardiovascular Surgery, Mitsui Memorial Hospital, Kandaizumicho-1, Chiyoda-ku, Tokyo, 101-8643, Japan. satonatanaka@mitsuihosp.or.jp
Abstract:
Werner's syndrome is a rare hereditary disorder that is characterized by premature aging. We report a case of off-pump coronary artery bypass grafting (OPCAB) in a 56-year-old man with Werner's syndrome. We used an endoscopic vessel-harvesting system to harvest great saphenous vein grafts (SVGs) because this system helps minimize surgical wounds. This is important because poor wound healing is a prominent feature of Werner's syndrome. Revascularization of the coronary arteries in this case was thought to improve his prognosis, although he had already outlived the average life-span of Werner's syndrome. A detailed examination of the cardiovascular system should be performed in patients with this disorder.
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