Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anatomy of the Eyeball

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Choroidal thickness of children's eyes with anisometropic and strabismic amblyopia.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2016

Same author

Re: Brodsky et al.: Intermittent exotropia and accommodative esotropia: distinct disorders or two ends of a spectrum? (Ophthalmology 2015;122:1543-6).

Ophthalmology·2016

Same author

Re: Hoyt C.: What is next in amblyopia treatment? (Ophthalmology 2015;122:871-3).

Ophthalmology·2015

Same author

Anomalous Vascular Patterns of the Optic Disc in Amblyopia.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2015

Same author

Atropine vs Patching.

JAMA ophthalmology·2015

Same author

Re: McKean-Cowdin et al.: prevalence of amblyopia or strabismus in asian and non-hispanic white preschool children (Ophthalmology 2013;120:2117-24).

Ophthalmology·2014

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

The Measurement and Treatment of Suppression in Amblyopia

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

Optic disc area and retinal area in amblyopia.

Philip Lempert¹

¹Cornell Medical Center, Ithaca, NY, USA.

Seminars in Ophthalmology

|December 17, 2008

Summary

This summary is machine-generated.

Hyperopic amblyopic eyes show increased retinal receptor areas and altered optic disc ratios compared to normal eyes, potentially explaining reduced visual acuity. This study highlights structural differences in amblyopic vision.

More Related Videos

Using Retinal Imaging to Study Dementia

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Jun 27, 2026

The Measurement and Treatment of Suppression in Amblyopia

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

Using Retinal Imaging to Study Dementia

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Area of Science:

Ophthalmology
Optometry
Vision Science

Background:

Hyperopia is a common refractive error.
Amblyopia, or
lazy eye,
affects visual development.
Understanding structural differences is key to diagnosing and treating visual impairments.

Purpose of the Study:

To compare the ratios of retinal area to optic disc rim area in hyperopic eyes.
Specifically comparing normal, strabismic, amblyopic, and fellow eyes.

Main Methods:

Magnification-corrected retinal photography and planimetry were used to measure neuroretinal rim areas.
Retinal area estimates were derived from axial lengths.
Subjects with bilateral hyperopia were included, excluding those with glaucoma or optic nerve atrophy.

Main Results:

Significant differences were found in the retinal area to optic disc rim area ratios between amblyopic eyes and normal, strabismic, or fellow eyes.
Hyperopic amblyopic eyes exhibited a 20% increase in retinal receptor areas compared to hyperopic eyes without amblyopia.
Dysplastic or asymmetric optic discs were more prevalent in amblyopic (56%) and strabismic (56%) eyes compared to normal eyes (13%).

Conclusions:

Increased retinal receptor area in amblyopic eyes may contribute to diminished visual acuity and impaired function.
Structural variations in the optic disc and retina are associated with amblyopia and strabismus.