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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Related Experiment Video

Updated: Jun 27, 2026

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model
10:32

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Published on: April 2, 2021

Retinopathy of prematurity.

Christin L Sylvester1

  • 1Children's Hospital of Pittsburgh, Division of Pediatric Ophthalmology, Pittsburgh, PA 15213, USA. sylvestercl@upmc.edu

Seminars in Ophthalmology
|December 17, 2008
PubMed
Summary

Retinopathy of prematurity (ROP) is a complex eye condition in premature infants. Recent research has improved understanding, screening, and treatment of ROP, with new therapies under investigation.

Area of Science:

  • Pediatric Ophthalmology
  • Neonatology
  • Ocular Development

Background:

  • Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
  • The pathophysiology of ROP is complex and continues to be elucidated.
  • Recent advancements have refined our understanding of ROP development.

Purpose of the Study:

  • To review current concepts in retinopathy of prematurity.
  • To highlight recent advances in ROP pathophysiology and clinical management.
  • To discuss emerging treatment modalities for ROP.

Main Methods:

  • Literature review of recent studies on retinopathy of prematurity.
  • Synthesis of current knowledge on ROP pathophysiology.
  • Analysis of updated screening criteria and treatment guidelines for ROP.

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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

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Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Related Experiment Videos

Last Updated: Jun 27, 2026

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model
10:32

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Published on: April 2, 2021

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

Transcutaneous Microcirculatory Imaging in Preterm Neonates
06:27

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Main Results:

  • A new understanding of ROP pathophysiology has emerged.
  • Clinical research has led to modified screening and treatment guidelines.
  • Novel treatments, including anti-angiogenic agents, are under investigation.

Conclusions:

  • Current concepts in ROP are rapidly evolving.
  • Advances in understanding ROP have improved clinical practice.
  • Future research holds promise for improved ROP management and outcomes.