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Post-thrombotic syndrome after total hip arthroplasty is uncommon
Michael J Mant1, Dean T Eurich, Donald B Russell
1Department of Medicine, Division of Hematology and Oncology, University of Alberta, Edmonton, Canada.
Acta Orthopaedica
|December 17, 2008
Summary
Post-thrombotic syndrome (PTS) is infrequent after total hip arthroplasty (THA) in patients receiving thromboprophylaxis. This suggests thromboprophylaxis may reduce symptomatic PTS, a potential complication of deep vein thrombosis (DVT).
Area of Science:
- Orthopedic Surgery
- Vascular Medicine
- Thrombosis Research
Background:
- Deep vein thrombosis (DVT) is a common complication following total hip arthroplasty (THA).
- Post-thrombotic syndrome (PTS) is a potential sequela of DVT, but its incidence after THA is not well-established.
- Limited data exists on the occurrence of PTS in patients undergoing THA.
Purpose of the Study:
- To investigate the incidence of symptomatic post-thrombotic syndrome (PTS) after total hip arthroplasty (THA).
- To identify potential predictors of PTS in patients who underwent THA and received thromboprophylaxis.
Main Methods:
- Prospective cohort study of 188 patients undergoing THA who had postoperative venography.
- PTS symptoms were assessed 2-4 years post-surgery using a validated scoring system.
- Exact logistic regression was used to explore potential predictors of PTS.
Main Results:
- 13% of patients had DVTs on venography; 6% developed symptoms consistent with PTS.
- Most affected limbs (15 of 19) did not have a postoperative DVT.
- No statistically significant predictors of PTS were identified.
Conclusions:
- Symptomatic PTS appears infrequent after THA when patients receive thromboprophylaxis.
- Findings support the potential benefit of thromboprophylaxis in reducing symptomatic PTS.
- Further research may clarify the long-term impact of DVT and thromboprophylaxis on PTS development.
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