Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Performance and nutrient composition of black soldier fly larvae fed diets with various protein concentrations throughout the life cycle.

Animal : an international journal of animal bioscience·2025

Same author

Growth dynamics and amorphous-to-crystalline phase transformation in natural nacre.

Nature communications·2023

Same author

Effects of restricted dietary phosphorus supply during the dry period on productivity and metabolism in dairy cows.

Journal of dairy science·2022

Same author

Laser ablation sample preparation for atom probe tomography and transmission electron microscopy.

Ultramicroscopy·2020

Same author

Effects of Escherichia coli strain Nissle 1917 on exercise-induced disruption of gastrointestinal integrity.

European journal of applied physiology·2020

Same author

Effects of ad libitum milk replacer feeding and butyrate supplementation on the epithelial growth and development of the gastrointestinal tract in Holstein calves.

Journal of dairy science·2019

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Nondestructive Monitoring of Degradable Scaffold-Based Tissue-Engineered Blood Vessel Development Using Optical Coherence Tomography

Nondestructive Monitoring of Degradable Scaffold-Based Tissue-Engineered Blood Vessel Development Using Optical Coherence Tomography

Published on: October 3, 2018

[Optical coherence tomography (OCT) to evaluate cartilage tissue engineering].

K Gavenis¹, R Schmitt, K Eder

¹Klinik für Orthopädie und Unfallchirurgie, Schwerpunkt Orthopädie, RWTH Aachen. kgavenis@ukaachen.de

Zeitschrift Fur Orthopadie Und Unfallchirurgie

|December 17, 2008

Summary

This summary is machine-generated.

Optical coherence tomography (OCT) effectively evaluated cartilage repair tissue in vitro, showing ultrastructural differences between collagen gels. OCT results correlated with histological staining, suggesting potential for in situ monitoring of tissue-engineered cartilage.

More Related Videos

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Related Experiment Videos

Last Updated: Jun 27, 2026

Nondestructive Monitoring of Degradable Scaffold-Based Tissue-Engineered Blood Vessel Development Using Optical Coherence Tomography

Nondestructive Monitoring of Degradable Scaffold-Based Tissue-Engineered Blood Vessel Development Using Optical Coherence Tomography

Published on: October 3, 2018

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Biomedical Engineering
Regenerative Medicine
Tissue Engineering

Background:

Hyaline cartilage defects pose significant clinical challenges.
Cell-seeded artificial matrix systems offer a promising therapeutic approach.
Advanced imaging modalities are needed for effective evaluation of cartilage repair.

Purpose of the Study:

To investigate hyaline cartilage defects treated with cell-seeded artificial matrix systems using optical coherence tomography (OCT).
To correlate OCT findings with conventional histological and immunocytochemical staining.
To assess the potential of OCT for evaluating tissue-engineered cartilage repair.

Main Methods:

Osteochondral blocks from knee replacement patients were used.
Chondral defects were filled with autologous chondrocyte-seeded collagen type I gels.
Specimens were cultured in vitro or implanted in nude mice, followed by OCT and histological analysis.

Main Results:

OCT allowed investigation of repair tissue up to 1.6 mm depth.
Ultrastructural features and differences between collagen gels were discernible via OCT.
OCT accurately evaluated the bonding zone between repair tissue and native cartilage, confirmed by histology.

Conclusions:

OCT is a viable method for evaluating in vitro cartilage repair tissue generated by tissue-engineered matrix systems.
OCT demonstrated ultrastructural differences between collagen gels and the bonding zone.
Future research may explore in situ monitoring of cartilage repair quality using OCT.