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Protective effects of misoprostol on carbon tetrachloride-induced liver damage in the rat
A A Mihas1, A K Markov, C Subramony
1Department of Medicine, University of Mississippi Medical Center, Jackson.
Pharmacology
|January 1, 1991
Abstract:
Effects of misoprostol on histologic and biochemical alterations caused by CCl4 were investigated in the rat. Misoprostol protected against CCl4-induced liver injury. A close correlation occurred between biochemical data and morphological changes. This hepatoprotective effect was observed only when misoprostol was given 30 min before CCl4.