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Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Intermolecular olefin functionalisation involving aryl radicals generated from arenediazonium salts
1Organische Chemie 1, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany. Markus.Heinrich@ch.tum.de
Chemistry (Weinheim an Der Bergstrasse, Germany)
|December 17, 2008
Summary
Recent advances in olefin functionalization reactions utilize aryl radicals from arenediazonium salts. These methods expand upon Meerwein arylation, enabling diverse functional group introductions onto olefins.
Area of Science:
- Organic Chemistry
- Synthetic Chemistry
Background:
- The Meerwein arylation is a classic reaction for coupling aryl halides to olefins.
- Arenediazonium salts are versatile precursors for generating aryl radicals.
Purpose of the Study:
- To review recent advancements in olefin functionalization using aryl radicals.
- To highlight new reaction types beyond traditional Meerwein arylation.
Main Methods:
- Generation of aryl radicals from arenediazonium salts.
- Application of these radicals in novel functionalization reactions with olefins.
Main Results:
- Development of new reaction pathways for olefin functionalization.
- Introduction of a wide array of functional groups at the halogen's position.
- Expanded substrate scope for olefinic compounds.
Conclusions:
- Modern synthetic strategies offer enhanced control and versatility in olefin functionalization.
- Arenediazonium salt-derived aryl radicals are key intermediates for novel transformations.
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