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Related Concept Videos

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Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...
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The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.

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Updated: Jun 27, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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[Nonfunctioning suprasellar ectopic pituitary adenoma. A case report].

Gohei So1, Tomoki Takeshita, Yoichi Morofuji

  • 1Department of Neurosurgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

No Shinkei Geka. Neurological Surgery
|December 18, 2008
PubMed
Summary

This case report details a rare nonfunctioning suprasellar ectopic pituitary adenoma in a 49-year-old man presenting with visual field defects. Surgical removal was challenging due to the tumor's attachment to the pituitary stalk.

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Area of Science:

  • Neuroendocrinology
  • Neurosurgery
  • Oncology

Background:

  • Ectopic pituitary adenomas are rare tumors arising outside the sella turcica.
  • Suprasellar ectopic pituitary adenomas are particularly uncommon, often presenting with mass effect symptoms.

Observation:

  • A 49-year-old male presented with a partial right visual field defect.
  • Neuroendocrinological tests revealed elevated adrenocorticotropic hormone and prolactin levels.
  • MRI demonstrated an enhancing suprasellar mass separate from a normal pituitary gland within the sella turcica.

Findings:

  • Histological examination confirmed a nonfunctioning pituitary adenoma in the suprasellar region.
  • The tumor was partially resected via craniotomy due to its adherence to the pituitary stalk.
  • This case highlights the diagnostic and surgical challenges of suprasellar ectopic pituitary adenomas.

Implications:

  • Reporting rare cases of ectopic pituitary adenomas aids in understanding their pathophysiology and clinical behavior.
  • Accurate diagnosis and surgical management are crucial for patients with these rare tumors.
  • Further research into the developmental origins and molecular characteristics of ectopic pituitary adenomas is warranted.