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[Experimental study on local attachment of Beriplast P membrane including MMC]
Y Takahashi1, S Minami, T Ohta
1Dept. of Surgery, Cancer Research Institute, Kanazawa University.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|August 1, 1991
Abstract:
We studied the effect of Beriplast P membrane including MMC (2 mg/ml) on human gastric carcinoma implanted in nude mouse (OSS) as a example of a shallow but broad lesion as with an early-stage local recurrence of rectal cancer and superficial gastric cancer. As a result, the resected tumor contact Beriplast P membrane including MMC after 3 days showed continuous necrotic lesions, from 1 to 2 mm in depth. No side effect was observed in nude mice. These results indicated that Beriplast P membrane including MMC is a useful chemotherapy against local cancerous lesion.