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Updated: Jun 27, 2026
Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
Management algorithms for stage IIIA non-small cell lung cancer with N2 node involvement
Frank Detterbeck1, Mithran S Sukumar
1Department of Surgery, Section of Thoracic Surgery, Yale University, 333 Cedar Street, FMB 128, P.O. Box 208062, New Haven, CT 06520, USA. frank.detterbeck@yale.edu
Abstract:
Stage IIIA non-small cell lung cancer (NSCLC) with N2 node involvement (IIIA[N2]) is a complex area characterized by much confusion and controversy, because data derived from a particular subgroup of IIIA(N2) often are inappropriately applied to another subgroup. The problem is not so much that stage IIIA(N2) encompasses a spectrum of disease, which is true in each stage of NSCLC. Rather, our ability to describe a patient cohort has been limited, and it is therefore often difficult to determine how and when to apply data from published studies. A simple, pragmatic approach is taken in this article to define algorithms for the management of these patients.
