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Peri-operative use of paracetamol
1South West School of Anaesthesia, Department of Anaesthetics, Royal Cornwall Hospital, Truro TR13LJ, UK. chrisoscier@hotmail.com
Abstract:
This article is a review of the peri-operative use of paracetamol. It reviews the pharmacology of paracetamol, highlighting new information about the mechanism of action, and examines its therapeutic use in the peri-operative period, focusing on efficacy, route of administration, and the use of a loading dose to improve early postoperative analgesia.
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