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Updated: Jun 27, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
Policies for manual removal of placenta at vaginal delivery: variations in timing within Europe
C Deneux-Tharaux1, A Macfarlane, C Winter
1INSERM, UMR S149, IFR 69, UPMC, Epidemiological Research Unit on Perinatal Health and Women's health, Hopital Tenon, Paris, France. cdeneux.u149@chusa.jussieu.fr
Abstract:
The length of the third stage of labour is a potential modifiable risk factor for postpartum haemorrhage at vaginal delivery, but there is no definitive evidence that early intervention to remove the placenta manually will prevent postpartum haemorrhage. We report a wide variation between countries in Europe in policies about the timing of manual removal of placenta. Two groups of countries with clearly divergent policies were identified. A randomised controlled trial is needed to provide definitive evidence on the risks and benefits of manual removal of placenta at different timings after vaginal delivery.

