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Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are themselves.

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How the combined approach of subjective and functional health improves the early identification of the older adults at risk of adverse events?

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Serious Health-Related Suffering Impairs Treatments and Survival in Older Patients With Cancer.

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Routinization: risk factor or marker of adjustment to negative health issues?

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Related Experiment Video

Updated: Jun 27, 2026

An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing
04:30

An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing

Published on: October 25, 2019

[Aging and routinization: a review].

Valérie Bergua1, Jean Bouisson

  • 1Laboratoire de psychologie, EA4139, Bordeaux. valerie.bergua@u-bordeaux2.fr

Psychologie & Neuropsychiatrie Du Vieillissement
|December 18, 2008
PubMed
Summary

Routinization in older adults involves consistent daily activities. Preference for routines is linked to psychological, functional, and cognitive vulnerabilities, impacting adaptation.

Area of Science:

  • Gerontology
  • Behavioral Science
  • Epidemiology

Context:

  • Routinization, the consistent performance of activities over time, is a key concept in understanding aging.
  • This study examines routinization from developmental and multidisciplinary perspectives, analyzing its evolution in recent research.
  • The functions of routinization are explored within a general model of disability.

Purpose:

  • To analyze the concept of routinization in the elderly.
  • To investigate the relationship between preference for routines and various vulnerability factors.
  • To discuss theoretical and clinical implications for identifying and managing adaptation difficulties in older adults.

Summary:

  • Routinization in the elderly, defined as consistent performance of environmental, behavioral, and social activities, is a complex phenomenon.

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Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

Related Experiment Videos

Last Updated: Jun 27, 2026

An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing
04:30

An Experimental Paradigm for Measuring the Effects of Ageing on Sentence Processing

Published on: October 25, 2019

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

  • The PAQUID epidemiological study revealed that preference for routines is associated with psychological, functional, and cognitive vulnerabilities.
  • This complexity extends beyond simple adaptive functioning.
  • Impact:

    • Highlights routinization's relevance for identifying vulnerability markers in the elderly.
    • Informs early detection, prevention, and management strategies for adaptation difficulties in aging populations.
    • Provides a framework for understanding the multifaceted nature of aging and disability.