Related Experiment Video

Updated: Jun 27, 2026

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm
04:56

Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm

Published on: August 1, 2025

Abdominal aortic aneurysm and significant coronary artery disease: strategies and options

Jean Marie Ruddy1, William Yarbrough, Thomas Brothers

  • 1Division of Vascular Surgery, Medical University of South Carolina, Charleston, SC 29425, USA. ruddy@musc.edu

Southern Medical Journal
|December 18, 2008
PubMed

Insights

Treating coronary artery disease (CAD) and abdominal aortic aneurysm (AAA) together is challenging. Staged or concomitant surgical repair, especially with minimally invasive options, shows promise for high-risk patients.

Area of Science:

  • Cardiovascular Surgery
  • Vascular Surgery
  • Interventional Cardiology

Background:

  • Managing patients with concurrent coronary artery disease (CAD) and abdominal aortic aneurysm (AAA) presents significant therapeutic challenges.
  • Optimal surgical strategies for these high-risk individuals are not well-defined.

Purpose of the Study:

  • To evaluate the safety and efficacy of different treatment approaches for patients with both CAD and AAA.
  • To compare outcomes of staged versus concomitant surgical interventions.

Main Methods:

  • Retrospective analysis of 32 patients with symptomatic or large AAA and significant CAD.
  • Interventions included staged coronary artery bypass grafting (CABG) followed by open AAA repair, staged coronary angioplasty before open AAA repair, staged CABG followed by endovascular aneurysm repair, and concomitant CABG and AAA repair.

Main Results:

  • Fifteen patients undergoing staged CABG then open AAA repair had a 13% mortality from aneurysm rupture.
  • No major complications occurred in patients receiving staged coronary angioplasty or staged CABG with endovascular AAA repair.
  • Ten patients undergoing concomitant CABG and AAA repair had a 10% intraoperative mortality, with no significant difference in morbidity compared to staged procedures.

Conclusions:

  • Minimally invasive coronary revascularization and aortic aneurysm repair are safe and effective for select high-risk patients.
  • Both staged and concomitant CABG and AAA repair are viable options, particularly when minimally invasive techniques are not feasible.
Abstract

More Related Videos

A Mouse Abdominal Aortic Aneurysm Model by Periadventitial Calcium Chloride and Elastase Infiltration05:07

A Mouse Abdominal Aortic Aneurysm Model by Periadventitial Calcium Chloride and Elastase Infiltration

Published on: August 2, 2024

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation09:32

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...