Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Validated Assessment Scale for the Auriculocephalic Angle in Asians.

Aesthetic plastic surgery·2026
Same author

Investigating the Pre-Implementation Facilitators and Barriers of the Implementation of the Fear of Recurrence Therapy (FORT) Intervention in Canadian Cancer Centers.

Psycho-oncology·2025
Same author

Recommendations for the use of Cohesive Polydensified Matrix filler technology for facial rejuvenation by the Latin American Expert Group.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2025
Same author

Fostering Competencies: A Scoping Review of Escape Rooms in Medical Education.

Medical science educator·2025
Same author

Multilayer Technique Using Calcium Hydroxylapatite Biostimulation With Different Dilutions in the Lateral Face.

Aesthetic surgery journal. Open forum·2025
Same author

Steps to improve the teaching of clinical reasoning in dermatology: A scoping review and proposal.

Skin health and disease·2024
Same journal

The Five Essential Concepts of Developmental Medicine: A Medical Paradigm for People with Developmental Disabilities.

Southern medical journal·2026
Same journal

α-Gal Syndrome in the South: Why We Need Treatment Trials, Not Just Tick Prevention.

Southern medical journal·2026
Same journal

Association between Main Pancreatic Duct Size, Comorbidities, and Fistula Formation after Whipple Procedure for Pancreatic Cancer.

Southern medical journal·2026
Same journal

Impact of Temperature Variation on Patients with Acute Severe Asthma.

Southern medical journal·2026
Same journal

Assessing the Accuracy and Reliability of ChatGPT-4 to Answer Clinical EHR Messages in Sports Medicine.

Southern medical journal·2026
Same journal

Diagnostic Utility and Clinical Implications of Inpatient Fecal Occult Blood Testing.

Southern medical journal·2026
See all related articles

Related Experiment Video

Updated: Jun 27, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Multiple painful cutaneous facial papules.

Claudia Hernandez1, Carmen M Rivera

  • 1Department of Dermatology, University of Illinois at Chicago, Chicago, IL 60612-7300, USA.

Southern Medical Journal
|December 18, 2008
PubMed
Summary
This summary is machine-generated.

Cutaneous piloleiomyoma, a rare skin condition, presents as facial papules. This syndrome is linked to uterine leiomyomas, leiomyosarcomas, and renal cell carcinoma, with fumarate hydratase gene mutations.

More Related Videos

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Related Experiment Videos

Last Updated: Jun 27, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Area of Science:

  • Dermatology
  • Oncology
  • Genetics

Background:

  • Piloleiomyomas are benign smooth muscle tumors.
  • Cutaneous piloleiomyomas are rare, often presenting as multiple papules.
  • Systemic associations are critical for comprehensive patient management.

Observation:

  • A 21-year-old female presented with linear, flesh-colored papules on her face.
  • The clinical presentation was consistent with cutaneous piloleiomyoma.

Findings:

  • The diagnosis of cutaneous piloleiomyoma was confirmed.
  • Associated conditions include uterine leiomyomas, leiomyosarcomas, and renal cell carcinoma.
  • Genetic analysis revealed mutations in the fumarate hydratase gene, characteristic of this syndrome.

Implications:

  • Physicians should be aware of the potential systemic associations of cutaneous piloleiomyoma.
  • Early recognition and screening for associated malignancies are crucial.
  • Understanding the genetic basis aids in diagnosis and counseling.