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Published on: August 24, 2019
Appendiceal mucocele. a retrospective analysis of 19 cases
B Papaziogas1, I Koutelidakis, P Tsiaousis
1Second Department of Surgery, Aristotle University of Thessaloniki Medical School, Fanariou str. 16, 551 33, Thessaloniki, Greece. papaziog@med.auth.gr
Background:
Appendiceal mucocele is an infrequent well-recognized entity that can present in a variety of clinical syndromes or can be asymptomatic and discovered incidentally.
Patients And Methods:
Nineteen patients with a diagnosis of primary appendiceal mucocele treated in our institution between January 1, 1987 and December 31, 2006 were included in this retrospective analysis.
Results:
The histological examination of the specimens revealed simple and hyperplastic appendiceal mucocele in nine cases (47%), mucinous appendiceal cystadenoma in eight cases (42%), and mucinous appendiceal cystadenocarcinoma in two cases (11%). Thirteen patients (68%) underwent appendectomy, five patients (26%) right colectomy, and two patients (6%) underwent right colectomy for invasive appendiceal cystadenocarcinoma and at the same time right nephrectomy and sigmoidectomy, respectively, for concomitant malignancy.
Conclusion:
Mucocele of the appendix may be related to a benign or malignant appendiceal process, leading to individualized diagnosis and treatment.
Insights
Appendiceal mucocele, a rare appendix condition, can be benign or malignant. Histopathology reveals various types, necessitating individualized treatment approaches based on diagnosis.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Appendiceal mucocele is an uncommon condition with diverse clinical presentations.
- It can be asymptomatic and discovered incidentally during imaging or surgery.
Purpose of the Study:
- To analyze the clinicopathological features and treatment outcomes of primary appendiceal mucocele.
- To determine the prevalence of benign and malignant appendiceal mucinous lesions.
Main Methods:
- Retrospective analysis of 19 patients diagnosed with primary appendiceal mucocele.
- Data collected from January 1, 1987, to December 31, 2006.
- Review of histological examinations and treatment records.
Main Results:
- Histology revealed simple/hyperplastic mucocele (47%), cystadenoma (42%), and cystadenocarcinoma (11%).
- Appendectomy was performed in 68% of patients; right colectomy in 26%.
- Two patients required extensive surgery for invasive appendiceal cystadenocarcinoma and concomitant malignancies.
Conclusions:
- Appendiceal mucocele encompasses a spectrum from benign to malignant processes.
- Diagnosis and treatment must be individualized based on the specific pathological findings.
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