Appendiceal mucocele. a retrospective analysis of 19 cases

B Papaziogas1, I Koutelidakis, P Tsiaousis

  • 1Second Department of Surgery, Aristotle University of Thessaloniki Medical School, Fanariou str. 16, 551 33, Thessaloniki, Greece. papaziog@med.auth.gr

Abstract

Insights

Appendiceal mucocele, a rare appendix condition, can be benign or malignant. Histopathology reveals various types, necessitating individualized treatment approaches based on diagnosis.

Area of Science:

  • Gastroenterology
  • Surgical Pathology
  • Oncology

Background:

  • Appendiceal mucocele is an uncommon condition with diverse clinical presentations.
  • It can be asymptomatic and discovered incidentally during imaging or surgery.

Purpose of the Study:

  • To analyze the clinicopathological features and treatment outcomes of primary appendiceal mucocele.
  • To determine the prevalence of benign and malignant appendiceal mucinous lesions.

Main Methods:

  • Retrospective analysis of 19 patients diagnosed with primary appendiceal mucocele.
  • Data collected from January 1, 1987, to December 31, 2006.
  • Review of histological examinations and treatment records.

Main Results:

  • Histology revealed simple/hyperplastic mucocele (47%), cystadenoma (42%), and cystadenocarcinoma (11%).
  • Appendectomy was performed in 68% of patients; right colectomy in 26%.
  • Two patients required extensive surgery for invasive appendiceal cystadenocarcinoma and concomitant malignancies.

Conclusions:

  • Appendiceal mucocele encompasses a spectrum from benign to malignant processes.
  • Diagnosis and treatment must be individualized based on the specific pathological findings.

Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...