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Related Experiment Video

Updated: Jun 27, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

The correlation in birth timing between singleton and twin gestations in the same mother.

Emily A Defranco1, Jen Jen Chang, George A Macones

  • 1Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0526, USA. emily.defranco@uc.edu

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|December 18, 2008
PubMed
Summary

The timing of twin births is significantly correlated with singleton births in the same mother. This finding may help predict birth timing for mothers at high risk of preterm birth, especially those with twin gestations.

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Published on: September 5, 2011

Area of Science:

  • Reproductive Health
  • Perinatology
  • Maternal-Fetal Medicine

Background:

  • Understanding factors influencing birth timing is crucial for optimizing neonatal outcomes.
  • Previous research has not fully explored the relationship between singleton and twin birth timing within the same maternal cohort.

Purpose of the Study:

  • To investigate the correlation between the birth timing of singleton and twin gestations in mothers who have experienced both.
  • To determine if shared influences affect the gestational age at birth for siblings born as singletons versus twins.

Main Methods:

  • Retrospective population-based cohort study utilizing birth certificate data from 1989-1997.
  • Analysis of 2222 women with at least one singleton and one twin birth.
  • Pearson correlation analysis to assess the relationship in gestational age between singleton and twin births.

Main Results:

  • A statistically significant positive correlation (r = 0.28, p < 0.001) was found between singleton and twin birth timing.
  • The mean difference in birth timing was 3.05 weeks.
  • The correlation remained significant after controlling for potential confounding factors (beta = 0.459, p < 0.001).

Conclusions:

  • A significant correlation exists in birth timing between singleton and twin pregnancies within the same mother.
  • Shared genetic, environmental, medical, and social factors may influence this observed correlation.
  • This finding has potential implications for predicting birth timing in high-risk pregnancies, particularly twin gestations.