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Updated: Jun 27, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
A case study of long-term cognitive and social functioning following a right temporal lobectomy in infancy
Catherine A Hynes1, Raymond A Mar
1School of Psychology, The University of Queensland, St Lucia, Australia. cahynes@gmail.com
Abstract:
We present the rare case of an adult patient, FS, who had a right anterior temporal lobe resection during infancy to treat intractable epilepsy, and underwent a cognitive evaluation 19 years later. Given the paucity of literature on long-term outcomes for infants who receive neurosurgery for epilepsy, this case provides valuable information for both clinicians and patients. What little literature exists on infant and child surgical outcomes for epilepsy suggests a variable course, with several areas of possible cognitive and social difficulty. FS's assessment at the age of 21 revealed only mild difficulties with memory, sequencing, and visual imagery, and spared intellectual functioning, working memory, problem-solving and social cognition, along with a high level of socioeconomic functioning. Thus, the case of FS suggests that neurosurgery during infancy is not necessarily associated with large-scale cognitive impairment, and furthermore, that high levels of functioning both educationally and vocationally are possible after surgical treatment of epilepsy in infancy.
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