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Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

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Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...

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Related Experiment Video

Updated: Jun 27, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

[Selective primary obesity prevention in children].

A Keller¹, A Klossek, R Gausche

¹Klinik und Poliklinik für Kinder und Jugendliche des Universitätsklinikums Leipzig AöR, Leipzig, Germany.

Deutsche Medizinische Wochenschrift (1946)

|December 19, 2008

Summary

Low threshold intervention for children with impending obesity successfully prevented BMI SDS increase. Early childhood interventions are key to preventing childhood obesity.

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Assessment of Child Anthropometry in a Large Epidemiologic Study

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Area of Science:

Pediatrics
Public Health
Nutrition Science

Context:

Childhood obesity is a growing public health concern, with rapid weight gain often starting between ages 4-5.
Early identification of children at risk is crucial for effective intervention.

Purpose:

To investigate the effectiveness of a low-threshold prevention program in mitigating BMI SDS increase in children with impending obesity.
To assess the impact of an age-adapted nutrition and exercise program on weight management in early childhood.

Summary:

A study involving 365 children (ages 4-7) with impending obesity randomly assigned them to an intervention or control group.
The intervention group, after opting in, showed stabilized BMI SDS, while the control group and non-participating intervention children experienced an increase.
Participants in the intervention group demonstrated reduced energy intake and improved protein consumption, indicating successful dietary changes.

Impact:

Low-threshold interventions in early childhood can effectively prevent the progression of obesity.
This approach highlights the potential for lifestyle modifications to manage weight in at-risk children.