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Published on: December 9, 2013
Sex differences in the hypertensive population with chronic ischemic heart disease
Vivencio Barrios1, Carlos Escobar, Vicente Bertomeu
1Department of Cardiology, Hospital Ramón y Cajal, Madrid, Spain. vbarriosa@meditex.es
Insights
Clinical management of chronic ischemic heart disease and hypertension shows sex differences. Men had better blood pressure and LDL-C control rates, despite women presenting with more comorbidities.
Area of Science:
- Cardiology
- Clinical Medicine
- Public Health
Background:
- Chronic ischemic heart disease and hypertension are significant clinical challenges.
- Understanding sex differences in management is crucial for optimizing patient outcomes.
- The CINHTIA survey provides insights into current clinical practices in Spain.
Purpose of the Study:
- To assess the clinical management of hypertensive patients with chronic ischemic heart disease.
- To examine sex differences in patient characteristics and treatment outcomes.
- To evaluate blood pressure and LDL-C control rates in this patient population.
Main Methods:
- A nationwide survey (CINHTIA) of 2024 patients with hypertension and chronic ischemic heart disease.
- Data collection on patient demographics, comorbidities, and management strategies.
- Analysis of sex-based differences in clinical presentation and control rates.
Main Results:
- Women were older, with higher BMI and more atrial fibrillation; men had higher rates of dyslipidemia, smoking, and peripheral arterial disease.
- Diabetes, left ventricular hypertrophy, and heart failure were more prevalent in women.
- Blood pressure and LDL-C control rates were significantly better in men (44.9% vs 30.5% and 33.0% vs 25.0%, respectively).
- Men underwent stress testing and coronary angiography more frequently.
Conclusions:
- Significant sex disparities exist in the clinical management of hypertensive patients with chronic ischemic heart disease.
- Despite poorer control rates, men received more diagnostic procedures.
- Further research is needed to address these sex differences and improve care for all patients.
Abstract:
Cardiopatía Isquémica Crónica e Hipertensión Arterial en la Práctica Clínica en España (CINHTIA) was a survey designed to assess the clinical management of hypertensive outpatients with chronic ischemic heart disease. Sex differences were examined. Blood pressures (BP) was considered controlled at levels of <140/90 or <130/80 mm Hg in diabetics (European Society of Hypertension/European Society of Cardiology 2003); low-density lipoprotein cholesterol (LDL-C) was considered controlled at levels <100 mg/dL (National Cholesterol Education Program Adult Treatment Panel III). In total, 2024 patients were included in the study. Women were older, with a higher body mass index and an increased prevalence of atrial fibrillation. Dyslipidemia, smoking, sedentary lifestyle, and peripheral arterial disease were more frequent in men. In contrast, diabetes, left ventricular hypertrophy, and heart failure were more common in women. BP and LDL-C control rates, although poor in both groups, were better in men (44.9% vs 30.5%, P<.001 and 33.0% vs 25.0%, P<.001, respectively). Stress testing and coronary angiography were more frequently performed in men.
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