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Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
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Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals
06:46

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Published on: January 5, 2016

[Psoriasis and HIV infection].

L Leal1, M Ribera, E Daudén

  • 1Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España. lorenalealcanosa@hotmail.com

Actas Dermo-Sifiliograficas
|December 19, 2008
PubMed
Summary

Psoriasis and human immunodeficiency virus (HIV) coinfection presents unique challenges for dermatologists. This review explores epidemiologic, pathogenic, and clinical aspects, alongside therapeutic strategies and drug interaction risks.

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Last Updated: Jun 27, 2026

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals
06:46

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Published on: January 5, 2016

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Context:

  • Psoriasis management is complicated by coinfection with human immunodeficiency virus (HIV).
  • Understanding the interplay between these conditions is crucial for effective patient care.
  • Dermatologists require specialized knowledge to address this complex comorbidity.

Purpose:

  • To review the epidemiologic, pathogenic, histopathologic, clinical, and prognostic aspects of psoriasis in HIV-infected individuals.
  • To outline differential diagnoses for skin conditions in this patient population.
  • To analyze current and emerging therapeutic options, including biologics, and discuss drug interaction risks.

Summary:

  • This review syntheses current knowledge on psoriasis coexisting with HIV infection.
  • It covers disease aspects from epidemiology to prognosis, differential diagnoses, and treatment strategies.
  • Therapeutic options range from topical treatments and retinoids to antiretroviral therapy, classic immunosuppressants, and novel biologic agents, with a focus on managing drug interactions.

Impact:

  • Provides dermatologists with a comprehensive guide to managing psoriasis in HIV-infected patients.
  • Informs clinical decision-making regarding safe and effective treatment strategies.
  • Highlights the importance of considering drug interactions in this complex patient group.