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Updated: Jun 27, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
04:45

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

[Rectal cancer margin].

M Rivoire1, M Malerba, A Gandini

  • 1Département de chirurgie, centre Léon-Bérard, université Claude-Bernard-Lyon-I, Lyon, France. Rivoire@lyon.fnclcc.fr

Bulletin Du Cancer
|December 19, 2008
PubMed
Summary
This summary is machine-generated.

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Rectal cancer treatment has advanced, with a focus shifting to the circumferential margin. This change, emphasizing total mesorectal excision, has reduced positive margins and recurrence rates, improving patient survival.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Surgical Oncology

Context:

  • Rectal cancer treatment has seen significant advancements over the past two decades.
  • Historically, the primary surgical focus for anal conservation in rectal cancer was the distal longitudinal margin.
  • Evolving understanding of prognostic factors has reshaped surgical strategies.

Purpose:

  • To highlight the paradigm shift in rectal cancer surgery.
  • To underscore the importance of the circumferential margin in predicting outcomes.
  • To document the impact of standardized surgical techniques on recurrence and survival.

Summary:

  • The prognostic significance of the circumferential margin in rectal cancer is now recognized.
  • This knowledge has driven the adoption of standardized surgical approaches, notably total mesorectal excision.

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Last Updated: Jun 27, 2026

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  • Consequently, rates of positive circumferential margins and locoregional recurrence have declined.

    • Impact:

    • Improved surgical standardization in rectal cancer management.
    • Reduced locoregional recurrence rates in rectal cancer patients.
    • Enhanced patient survival following rectal cancer treatment.