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Updated: Jun 27, 2026
04:34
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Ewing's sarcoma of the hand.
O A Anakwenze1, W L Parker, L E Wold
1Mayo Clinic College of Medicine, Department of Orthopedic Surgery, Rochester, MN 55905, USA.
The Journal of Hand Surgery, European Volume
|December 19, 2008
Summary
Ewing sarcoma of the hand is rare but treatable. Surgical excision and chemotherapy offer good outcomes, with radiation therapy potentially improving local control in hand Ewing sarcoma cases.
Area of Science:
- Orthopedic Oncology
- Skeletal Oncology
- Pediatric Oncology
Background:
- Ewing sarcoma is a rare bone cancer predominantly affecting children and young adults.
- Hand involvement is exceptionally uncommon, posing unique diagnostic and therapeutic challenges.
Purpose of the Study:
- To report outcomes of Ewing sarcoma originating in the hand.
- To evaluate the efficacy of multimodal treatment including surgery, chemotherapy, and radiation therapy.
Main Methods:
- Retrospective case review of five patients diagnosed with hand Ewing sarcoma since 1995.
- Analysis of treatment modalities: wide surgical excision, chemotherapy, and radiation therapy.
- Assessment of local recurrence, metastasis development, and patient survival.
Main Results:
- No local recurrences were observed in any of the five patients.
- Three patients achieved disease-free survival for 4-12 years post-treatment.
- Two patients developed distant metastases and succumbed to the disease; neither received local postoperative radiation therapy.
Conclusions:
- Multimodal therapy, including wide surgical excision and chemotherapy, is crucial for managing hand Ewing sarcoma.
- Local postoperative radiation therapy may play a role in preventing recurrence and improving outcomes.
- Early and aggressive treatment is vital for improving survival rates in this rare malignancy.
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