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Related Experiment Video

Updated: Jun 27, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Modified prostate volume algorithm improves transrectal US volume estimation in men presenting for prostate

Peter J MacMahon¹, Ann-Marie Kennedy, Darra T Murphy

¹Department of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.

|December 19, 2008

Summary

This summary is machine-generated.

A new prostate volume formula, accounting for bullet-like shapes, significantly improves accuracy over the standard ellipsoid method for brachytherapy patients. This enhanced prostate cancer treatment planning tool offers more precise measurements.

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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Area of Science:

Urology
Medical Imaging
Oncology

Background:

Accurate prostate volume estimation is crucial for effective brachytherapy planning.
The conventional transrectal ultrasonographic (US) prolate ellipsoid formula is widely used but may lack precision.
Prostate gland morphology can vary, potentially impacting volume calculation accuracy.

Purpose of the Study:

To assess the accuracy of the standard US prostate volume formula.
To develop and validate a more accurate formula based on prostate shape observed at planimetry.
To improve volume estimation for the majority of prostate glands undergoing brachytherapy.

Main Methods:

Retrospective analysis of 138 patients undergoing prostate brachytherapy.
Comparison of conventional prolate ellipsoid formula volumes with a reference standard derived from planimetry.
Assessment of prostate shape using 3D volume-rendering and identification of the best-fit mathematical formula.

Main Results:

The majority of prostate glands exhibited a bullet shape, deviating from the ellipsoid model.
The conventional formula underestimated prostate volume by an average of 17%.
A modified formula (length x height x width x [pi/4.8]) improved accuracy, with 75% of volumes within 10% of planimetric measurements, especially for smaller glands (<55 cm³).

Conclusions:

A modified prostate volume formula, incorporating a bullet shape, offers superior accuracy for volume measurement in men undergoing brachytherapy.
This improved accuracy is particularly notable for prostates smaller than 55 cm³.
The findings suggest a revised approach to prostate volume calculation for enhanced treatment planning.