Related Experiment Video
Updated: Jun 27, 2026

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
Published on: February 9, 2020
Why and how do tumors stimulate lymphangiogenesis?
1Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 17177 Stockholm, Sweden. Yihai.cao@ki.se
Abstract:
Accumulating evidence shows that a subset of solid tumors stimulates lymphangiogenesis, which mediates lymphatic metastasis. Unlike blood vessels, lymphatics do not provide oxygen and nutrients that are essential for tumor growth. Why then do tumors induce lymphatic vessel growth? Do lymphatics play an active role in promoting tumor growth? Is tumor lymphangiogenesis secondary to blood vessel angiogenesis? How do tumors induce lymphangiogenesis? This review article focuses on discussing these fundamental issues related to cancer metastasis.
More Related Videos
09:03Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
07:45Draining Lymph Node Metastasis Model for Assessing the Dynamics of Antigen-Specific CD8+ T Cells During Tumorigenesis
Published on: January 26, 2024
Related Concept Videos
The Tumor Microenvironment
Regulation of Angiogenesis and Blood Supply
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Mechanism of Angiogenesis
Cancer
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...