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Updated: Sep 14, 2026

Laparoscopic S7 Hepatectomy with Positive Fluorescence Staining
Published on: May 9, 2025
[The efficacy of preoperative portal vein embolization for extended hepatectomy: a meta-analysis]
Wen-yi Zhao1, Meng Luo, Yong-wei Sun
1Department of General Surgery, Ren Ji Hospital, Shanghai Jiao Tong University of Medicine, Shanghai 200127, China.
Objective:
To investigate the clinical value of preoperative portal vein embolization (PVE) for extended hepatectomy.
Methods:
A comprehensive Pubmed, Medline and Ovid database search to identify all registered literature on portal vein embolization. Meta-analysis was performed to assess the result of PVE.
Results:
A total of 9 literatures provided data sufficiently enough for analysis involving in 494 patients. The results showed that postoperative liver failure was higher in the non-PVE group than the PVE group, but there was no difference in postoperative mortality between the PVE and non-PVE group; in sub-category analysis of hepatocellular carcinoma and liver metastasis of colorectal cancer, there was no difference in postoperative 1, 3 and 5-year survival rate between the PVE group and non-PVE group; 1 literature about liver metastasis of colorectal cancer show there was significant difference in postoperative metastasis between the PVE and non-PVE group; several patients after PVE didn't performed hepatectomy due to disease progress.
Conclusions:
PVE is a safe and effective procedure to prevent postresection liver failure due to insufficient liver remnant, but surgeon should be cautious to choose the patient for PVE.

