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Updated: Jun 27, 2026

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
Published on: September 1, 2015
CD4+/CD56+ Hematodermic neoplasm (plasmacytoid dendritic cell tumor)
Michael Shiman1, Robb Marchione, Carlos Ricotti
1Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Abstract:
A 60-year-old male presented with multiple, purplish-red, nodules and plaques. After a complete work-up, he was diagnosed with CD4+/CD56+ hematodermic neoplasm. We review the clinical, pathological, and immunohistochemical features of this disease. CD4+/CD56+ hematodermic neoplasm, which is also known as blastic natural killer-cell lymphoma, is a rare, aggressive neoplasm with a strong predilection for skin involvement.
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