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Updated: Jun 27, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
[Calculation of the left ventricular ejection fraction. Comparison between 4 different instruments]
R Puchal Añé1, S Guirao Marín, A Domènech Vilardell
1Servicio de Medicina Nuclear, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. rpuchal@csub.scs.es
Aim:
The aim of this study was to analyse the relationship between left ventricular ejection fractions (EF) obtained using four different instruments.
Material And Methods:
Eighty-five EF values were analysed. Gated acquisition was performed with the same gammacamera (SOPHA) using 99mTc-labelled red cells. Each EF was obtained using four processing systems: NXT (SOPHA), Entegra (Gems), Odyssey (Philips) and Esoft (Siemens), always working in automated mode. The paired student's t-test, Spearman correlation and Bland-Altman analysis were used to compare methods, and Deming regression was applied.
Results:
Mean values and standard deviations for each program were: NXT: 61 +/- 9; Entegra: 60 +/- 10; Odyssey: 60 +/- 9; Esoft: 60 +/- 10. Although no significant differences were found as a whole and the values were linearly related, the methods are not interchangeable.
Conclusions:
The same program should be used in the follow-up of each patient, which is now easily achievable by means of the DICOM standard.

