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Updated: Jun 27, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats

Published on: December 13, 2019

[Calculation of the left ventricular ejection fraction. Comparison between 4 different instruments].

R Puchal Añé¹, S Guirao Marín, A Domènech Vilardell

¹Servicio de Medicina Nuclear, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. rpuchal@csub.scs.es

Revista Espanola De Medicina Nuclear

|December 20, 2008

Summary

This summary is machine-generated.

Four instruments for measuring left ventricular ejection fraction (EF) showed similar results but are not interchangeable. Consistent use of the same EF measurement program is recommended for patient follow-up.

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Area of Science:

Cardiology
Medical Imaging
Nuclear Medicine

Background:

Left ventricular ejection fraction (EF) is a critical indicator of cardiac function.
Accurate EF measurement is essential for diagnosing and managing heart conditions.
Standardization of EF measurement across different imaging systems is a clinical challenge.

Purpose of the Study:

To analyze the relationship between left ventricular ejection fractions (EF) obtained using four different processing systems.
To evaluate the interchangeability of EF measurements from NXT, Entegra, Odyssey, and Esoft systems.

Main Methods:

Eighty-five EF values were analyzed from gated acquisition using a SOPHA gammacamera and 99mTc-labelled red cells.
EF was calculated using four automated processing systems: NXT (SOPHA), Entegra (Gems), Odyssey (Philips), and Esoft (Siemens).
Statistical analysis included paired Student's t-test, Spearman correlation, Bland-Altman analysis, and Deming regression.

Main Results:

Mean EF values were similar across all four systems (NXT: 61±9, Entegra: 60±10, Odyssey: 60±9, Esoft: 60±10).
While EF values were linearly related and showed no significant overall differences, the methods were found to be non-interchangeable.
Variability between systems suggests potential discrepancies in long-term patient monitoring.

Conclusions:

Consistent use of the same EF measurement program is crucial for accurate patient follow-up.
The DICOM standard facilitates the consistent application of specific EF measurement programs across different institutions.