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Updated: Jun 27, 2026
12:25
Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
Denmark: botulism in an infant or infant botulism?
A Paerregaard1, O Angen, M Lisby
1Department of Paediatrics, Hvidovre, Denmark. anders.paerregaard@hvh.regionh.dk
Summary
A Danish infant diagnosed with botulism showed improvement after receiving antiserum. This case highlights infant botulism and the possibility of foodborne neurotoxin acquisition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Toxicology
Background:
- Infant botulism is a rare but serious condition caused by the bacterium Clostridium botulinum.
- Early diagnosis and treatment are crucial for patient recovery.
Observation:
- A 4.5-month-old infant presented with progressive weakness, ptosis, and loss of reflexes.
- Clinical signs were highly suggestive of botulism.
Findings:
- Botulism was confirmed via serum bioassay.
- The infant's condition improved after administration of botulism antiserum.
Implications:
- This case underscores the importance of recognizing infant botulism symptoms.
- It also raises awareness about potential foodborne neurotoxin sources in infants.
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