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Updated: Jun 27, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
The "dysplastic" nevus
Robert J Friedman1, Michele J Farber, Melanie A Warycha
1Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA. rfriedmanmdceo@hotmail.com
Clinics in Dermatology
|December 20, 2008
Summary
Dysplastic nevi are linked to increased melanoma risk, though their significance and management remain debated. Research covers their history, genetics, and clinical features, guiding current surveillance and biopsy recommendations.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Dysplastic nevi are increasingly recognized clinically.
- Evidence suggests a correlation between dysplastic nevi and a higher risk of melanoma development.
- Contention exists regarding the clinical significance and precise definition of dysplastic nevi.
Purpose of the Study:
- To provide a comprehensive overview of dysplastic nevi.
- To examine the history, epidemiology, genetics, and clinical/histologic features of dysplastic nevi.
- To discuss current clinical management procedures and future technological impacts.
Main Methods:
- Literature review and synthesis of existing research on dysplastic nevi.
- Analysis of historical data, epidemiological studies, and genetic research.
- Examination of clinical and histological diagnostic criteria and management guidelines.
Main Results:
- Dysplastic nevi were first described in 1978.
- Significant research exists on the epidemiology and genetics of dysplastic nevi.
- Disagreement persists on the clinical management and histological definition of dysplastic nevi.
Conclusions:
- Current management involves preventative measures like sun protection and surveillance.
- Biopsies are recommended for suspicious lesions.
- Emerging technologies, such as computer-vision systems, may influence future treatment paradigms for dysplastic nevi.
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