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Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...
X-ray Crystallography02:18

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

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High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
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Hard X-ray phase-contrast imaging with the Compact Light Source based on inverse Compton X-rays.

Martin Bech1, Oliver Bunk, Christian David

  • 1University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark. bech@fys.ku.dk

Journal of Synchrotron Radiation
|December 20, 2008
PubMed
Summary

The Compact Light Source, a novel small-size synchrotron, produced its first imaging results using inverse Compton X-rays. Its highly coherent X-ray beam is ideal for advanced grating-based differential phase-contrast imaging.

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Area of Science:

  • Medical Imaging
  • Synchrotron Radiation
  • X-ray Optics

Background:

  • Small-size synchrotrons offer potential for compact X-ray sources.
  • Inverse Compton scattering is a method for generating high-energy photons.
  • Differential phase-contrast imaging requires highly coherent X-ray beams.

Purpose of the Study:

  • To report the first imaging results from a novel small-size synchrotron.
  • To characterize the X-ray beam produced by the Compact Light Source.
  • To evaluate the suitability of the Compact Light Source for advanced imaging techniques.

Main Methods:

  • Utilized a newly developed Compact Light Source (CLS).
  • Generated inverse Compton X-rays at the intersection of laser and electron beams.
  • Employed a grating-based differential phase-contrast imaging method.

Main Results:

  • Obtained the first imaging results from the CLS.
  • The CLS produced a highly coherent cone beam with low angular divergence.
  • The X-ray beam exhibited a few percent energy spread, suitable for phase-contrast imaging.

Conclusions:

  • The Compact Light Source is a viable small-size synchrotron for generating high-quality X-rays.
  • The CLS is well-suited for advanced imaging methods like differential phase-contrast imaging.
  • This demonstrates a significant step towards accessible, high-performance X-ray imaging.