Related Experiment Video
Updated: Jun 27, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Clinical analysis of risk factors related to recurrent chronic subdural hematoma
Byung-Soo Ko1, Jung-Kil Lee, Bo-Ra Seo
1Department of Neurosurgery, Chonnam National University Hospital & Medical School, Gwangju, Korea.
Insights
High- and mixed-density chronic subdural hematomas (CSDH) on CT scans and bleeding tendencies are risk factors for recurrence after burr hole drainage. Delayed surgery may be considered for these patients.
Area of Science:
- Neurosurgery
- Radiology
Background:
- Burr hole drainage is a common treatment for chronic subdural hematoma (CSH).
- Recurrence rates after surgery vary significantly (3.7-30%).
Purpose of the Study:
- To identify risk factors for CSDH recurrence after one burr hole drainage.
Main Methods:
- Retrospective analysis of 255 patients who underwent one burr hole drainage for CSDH.
- Evaluation of demographic, clinical, and radiologic factors.
Main Results:
- High- and mixed-density CSDH on CT scans were associated with significantly higher recurrence rates (p<0.001).
- Bleeding tendencies (e.g., leukemia, liver disease, chronic renal failure) were also significantly linked to recurrence (p=0.037).
Conclusions:
- High- and mixed-density CSDH on CT scans predict higher recurrence risk.
- Consider delaying surgery for these patients unless severe symptoms are present.
- Reoperation at the previous burr hole site is a preferred treatment for recurrent CSDH.
Objective:
Burr hole drainage has been widely used to treat chronic subdural hematoma (CSDH). However, the incidence of recurrent CSDH varies from 3.7 to 30% after surgery. The authors attempted to elucidate the risk factors associated with the recurrence of CSDH in one burr hole drainage technique.
Methods:
A total of 255 consecutive cases who underwent one burr hole drainage for CSDH were included in this study. Twenty-four patients (9.4%) underwent a repeated operation because of the recurrence of CSDH. We analyzed retrospectively the demographic, clinical and radiologic factors associated with the recurrence of CSDH.
Results:
In this study, two risk factors were found to be independently associated with the recurrence of CSDH. The incidence of CSDH recurrence in the high- and mixed-density groups was significantly higher than those in the low- and iso-density groups (p<0.001). Bleeding tendency such as in leukemia, liver disease and chronic renal failure was also significantly associated with recurrence of CSDH (p=0.037).
Conclusion:
These results suggest that high- and mixed- density shown on computed tomographic scan was closely relates with a high incidence of recurrence. Therefore, the operation could be delayed in those cases unless severe symptoms or signs are present. Reoperation using the previous burr hole site is a preferred modality to treat the recurrent CSDH.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Brain Abscess l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Increased Intracranial Pressure l: Introduction
