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Related Experiment Video

Updated: Jun 27, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

[Lymphatic mapping in cervical cancer].

L Sevcík¹, J Klát, P Gráf

¹Porodnicko-Gynekologická Klinika FN Ostrava. libor.sevcik@fnspo.cz

Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti

|December 23, 2008

Summary

This summary is machine-generated.

This study demonstrates that intraoperative sentinel lymph node (SLN) detection using a gamma probe and blue dye is a feasible and accurate method for identifying lymphatic spread in early-stage cervical cancer.

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Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO⁺ and Light Sheet Fluorescence Microscopy

Published on: May 22, 2020

Area of Science:

Oncology
Surgical Pathology
Nuclear Medicine

Context:

Cervical cancer staging requires accurate assessment of lymph node involvement.
Sentinel lymph node (SLN) biopsy is a crucial diagnostic procedure.
Minimally invasive detection methods are sought to improve accuracy and patient outcomes.

Purpose:

To evaluate the feasibility, safety, and accuracy of intraoperative SLN detection.
To assess the efficacy of combining technetium-99m-labeled nanocolloid with blue dye for SLN identification.
To analyze the detection rate and diagnostic performance in relation to tumor volume.

Summary:

A prospective study included 106 cervical cancer patients undergoing SLN detection using gamma probe and blue dye.
Lymphoscintigraphy with 99mTc-nanocolloid and intraoperative identification via blue dye and gamma probe were performed.
A high SLN detection rate (94.3% per patient) was achieved, with metastasis detected in 36.8% of patients.

Impact:

This combined technique offers a feasible, safe, and accurate approach for staging early-stage cervical cancer (IA2-IB1).
It aids in identifying lymphatic spread, potentially influencing treatment decisions and patient prognosis.
The method's accuracy, with a high negative predictive value, supports its clinical utility.