Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin

Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin

Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
The binding of dantrolene to the RYR1...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Interdisciplinary consensus statements on imaging of scaphoid fractures.

European radiology·2026

Same author

Surgeon preferences in the treatment of thumb carpometacarpal osteoarthritis.

World journal of orthopedics·2024

Same author

The Perceived Value of Same-Sex or Same-Race Mentors and Role Models in Academic Medicine.

Journal of surgical orthopaedic advances·2024

Same author

Current trends in the prevention of adhesions after zone 2 flexor tendon repair.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2024

Same author

Advanced Arthritis of the Carpus: Preoperative Planning Practices of 337 Hand Surgeons.

Journal of wrist surgery·2024

Same author

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.

Osteoarthritis and cartilage·2023

Same journal

Current Concepts in Perioperative Guidance and Outcomes in Hand Surgery Patients Taking Glucagon-Like Peptide-1 Receptor Agonists.

The Journal of hand surgery·2026

Same journal

Mesenchymal Stem Cell-Derived Exosomes Combined With 3-Dimensional Hyaluronan-Based Scaffold Promote Tendon-to-Bone Tunnel Healing.

The Journal of hand surgery·2026

Same journal

The Diagnosis and Management of Clenched Fist Syndrome.

The Journal of hand surgery·2026

Same journal

Ultrasound-Assisted Thin Posteromedial Thigh Free Flap for Coverage of Hand and Upper-Extremity Wounds.

The Journal of hand surgery·2026

Same journal

Comparison of One- and Two-knot Techniques in Eight-Strand Flexor Tendon Repair Using Looped Sutures: A Biomechanical Study in a Porcine Model.

The Journal of hand surgery·2026

Same journal

Biomechanical Comparison of Metal Versus Suture and Screw Tension Band Technique for Olecranon Fractures.

The Journal of hand surgery·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Steroid injection for lateral epicondylitis

Robert M Szabo¹

¹School of Medicine, University of California-Davis, Sacramento, CA 95817, USA. rmszabo@ucdavis.edu

The Journal of Hand Surgery

|December 23, 2008

Summary

No abstract available in PubMed .

More Related Videos

A Protocol to Acquire the Degenerative Tenocyte from Humans

A Protocol to Acquire the Degenerative Tenocyte from Humans

Published on: June 9, 2018

Related Experiment Videos

Last Updated: Jun 27, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

A Protocol to Acquire the Degenerative Tenocyte from Humans

A Protocol to Acquire the Degenerative Tenocyte from Humans

Published on: June 9, 2018