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Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
06:45

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

Imaging the penumbra - strategies to detect tissue at risk after ischemic stroke

M Ebinger1, D A De Silva, S Christensen

  • 1Department of Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria 3050, Australia.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|December 23, 2008
PubMed

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...