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Related Concept Videos

Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
Spongy Bone01:09

Spongy Bone

All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the neck...

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Related Experiment Video

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Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
09:25

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

Periosteal chondrosarcoma.

Skander Chaabane1, Mouna Chelli Bouaziz, Cyrine Drissi

  • 1Department of Radiology, Institut Kassab d'orthopédie, Ksar Said, Tunis 2010, Tunisia. skanderchaabane@yahoo.fr

AJR. American Journal of Roentgenology
|December 23, 2008
PubMed
Summary
This summary is machine-generated.

Periosteal chondrosarcoma, a rare bone tumor, has distinct imaging features on radiography, CT, and MRI. Early identification is crucial for excellent prognosis with surgical treatment.

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Area of Science:

  • Orthopedic Oncology
  • Radiology
  • Skeletal Imaging

Background:

  • Periosteal chondrosarcoma is a rare, low-grade malignant cartilaginous tumor.
  • It originates from the external surface of bone.

Purpose of the Study:

  • To identify the typical imaging features of periosteal chondrosarcoma.
  • To differentiate it from other surface bone tumors using radiography, CT, and MRI.

Main Methods:

  • Review of imaging findings (radiography, CT, MRI) in cases of periosteal chondrosarcoma.
  • Correlation of imaging features with histopathological diagnosis.

Main Results:

  • Specific imaging characteristics of periosteal chondrosarcoma were identified across different modalities.
  • Key features aiding in differentiation from other bone surface tumors were highlighted.

Conclusions:

  • Periosteal chondrosarcoma exhibits characteristic imaging features on radiography, CT, and MRI.
  • Accurate recognition and differentiation from other surface tumors are vital.
  • Prognosis is excellent following appropriate local surgical excision.