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Updated: Jun 27, 2026
Manual Segmentation of the Human Choroid Plexus Using Brain MRI
Published on: December 15, 2023
Spectrum of choroid plexus lesions in children
Ramin M Naeini1, Jeong Hyun Yoo, Jill V Hunter
1Department of Radiology, Baylor College of Medicine, One Baylor Plaza, MailStop 360, Houston, TX 77030, USA. naeini@bcm.edu
Insights
This review covers choroid plexus embryology and its associated pediatric disorders, detailing their characteristic radiologic appearances for better diagnosis. Understanding these conditions is crucial for identifying various congenital abnormalities and pathologies within the central nervous system.
Area of Science:
- Developmental biology
- Pediatric neurology
- Neuroradiology
Background:
- The choroid plexus, a key structure in the central nervous system (CNS), plays a vital role in cerebrospinal fluid production.
- Disorders affecting the choroid plexus can arise from congenital abnormalities or acquired pathologies, impacting pediatric neurological health.
Purpose of the Study:
- To comprehensively review the embryological development of the choroid plexus.
- To delineate the spectrum of pediatric disorders involving the choroid plexus.
- To illustrate the characteristic radiologic features associated with these choroid plexus conditions.
Main Methods:
- Literature review focusing on embryology of the choroid plexus.
- Analysis of pediatric cases with choroid plexus abnormalities.
- Correlation of clinical and imaging findings.
Main Results:
- Detailed description of choroid plexus embryogenesis.
- Categorization of various congenital and acquired pediatric disorders.
- Exemplification of radiologic manifestations including cysts, neoplasms, infections, and vascular malformations.
Conclusions:
- The choroid plexus is a significant site for diverse congenital and pathological conditions in children.
- Recognition of specific radiologic features aids in diagnosing choroid plexus abnormalities.
- These abnormalities encompass neoplasms, infections, inflammatory processes, cysts, and vascular malformations.
Objective:
The aim of this article is to review the embryology of the choroid plexus and the spectrum of disorders involving the choroid plexus in children and to illustrate their radiologic features.
Conclusion:
The choroid plexus is an important part of the CNS that can be the primary or secondary location for many congenital abnormalities or pathologic conditions such as neoplasms, infections, inflammatory processes, cysts, and vascular malformations.
