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Related Experiment Videos

Screening recommendations for gestational diabetes mellitus.

L Cousins1, L Baxi, R Chez

  • 1Sharp Perinatal Center, San Diego, CA 92123.

American Journal of Obstetrics and Gynecology
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

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The best gestational diabetes mellitus screening uses a 1-hour plasma glucose test after a 50 gm oral glucose challenge. Universal screening during pregnancy with a threshold of 140 mg/dl is recommended for simplicity and reduced morbidity.

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Clinical Chemistry

Background:

  • Gestational diabetes mellitus (GDM) poses risks to both mother and fetus.
  • Effective screening is crucial for early detection and management of GDM.
  • Current screening protocols vary, necessitating a standardized approach.

Purpose of the Study:

  • To identify the optimal screening test for gestational diabetes mellitus.
  • To establish evidence-based recommendations for GDM screening protocols.
  • To advocate for universal GDM screening in pregnancy.

Main Methods:

  • Comprehensive review of existing literature on GDM screening.
  • Analysis of extensive clinical experiences from multiple centers.
  • Evaluation of screening test performance based on sensitivity and specificity.

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Main Results:

  • A 1-hour plasma glucose level following a 50 gm oral glucose challenge is identified as the most effective screening method.
  • A screening threshold of 140 mg/dl is proposed to maintain high sensitivity.
  • Universal screening at least once during pregnancy is supported.

Conclusions:

  • The 1-hour oral glucose challenge test (GCT) is the recommended screening test for GDM.
  • Universal screening simplifies protocols and reduces associated maternal and fetal morbidity.
  • Adherence to the proposed threshold ensures diagnostic sensitivity for GDM.