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Published on: August 15, 2025
Inflammatory pseudotumor in the mandible.
Jung-Hwan Oh1, Jin-Hyuk Yim, Byung-Wook Yoon
1Department of Oral and Maxillofacial Surgery, Kyung Hee University Dental School, Seoul, Republic of Korea.
The Journal of Craniofacial Surgery
|December 23, 2008
Summary
Inflammatory pseudotumor (IPT) is a rare, benign lesion that can mimic malignancy, especially in the maxillofacial region. Histological examination is key for diagnosis, preventing misdiagnosis and unnecessary radical procedures.
Area of Science:
- Oral and Maxillofacial Surgery
- Pathology
- Oncology
Background:
- Inflammatory pseudotumor (IPT) is a rare benign lesion of unclear etiology.
- IPT in the maxillofacial region is exceptionally rare and often misdiagnosed as malignancy.
- Accurate diagnosis is crucial due to IPT's potential to mimic invasive tumors.
Observation:
- This report details an aggressive case of inflammatory pseudotumor involving the mandible.
- The lesion presented features that mimicked invasive malignant neoplasms.
- Histological examination revealed a composition of histiocytes, plasma cells, and lymphocytes.
Findings:
- Histopathological analysis is the cornerstone for diagnosing inflammatory pseudotumor.
- The cellular composition includes histiocytes, plasma cells, and lymphocytes.
- The study reviews literature on maxillofacial inflammatory pseudotumors.
Implications:
- Considering inflammatory pseudotumor before radical procedures can prevent overtreatment.
- Early and accurate diagnosis of IPT is essential for appropriate patient management.
- This case highlights the importance of differential diagnosis in maxillofacial pathology.
