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Related Concept Videos

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
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Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Abnormal Proliferation

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Loss of Tumor Suppressor Gene Functions01:12

Loss of Tumor Suppressor Gene Functions

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Kimura disease.

Emin Karaman1, Huseyin Isildak, Alper Ozdilek

  • 1From the Otolaryngology Head and Neck Surgery Department of Cerrahpasa Medical School, Istanbul University, Istanbul.

The Journal of Craniofacial Surgery
|December 23, 2008
PubMed
Summary

Kimura disease (KD) is a rare inflammatory condition causing neck masses. Complete surgical resection of the lesion can be an effective treatment, preventing recurrence in patients with this vascular tumor.

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Area of Science:

  • Otolaryngology
  • Pathology
  • Immunology

Background:

  • Kimura disease (KD) is a chronic inflammatory disorder of unknown cause.
  • It typically presents as painless unilateral cervical lymphadenopathy or head/neck subcutaneous masses.
  • KD is an unusual vascular tumor often affecting young adults, with potential for recurrence after excision.

Observation:

  • A case study of a 28-year-old male patient with a unilateral cervical mass is presented.
  • The patient was diagnosed with Kimura disease.
  • A complete excisional resection of the mass was performed.

Findings:

  • The patient showed no signs of disease recurrence post-surgery.
  • This suggests that complete surgical resection can be a definitive treatment for Kimura disease.
  • The case highlights the importance of considering KD in patients with neck masses and eosinophilia.

Implications:

  • Surgical management is a viable option for treating Kimura disease.
  • Otolaryngologists should include KD in their differential diagnosis for neck masses, especially when accompanied by eosinophilia.
  • Early and accurate diagnosis is crucial for effective management and to prevent potential complications, such as nephritic syndrome.