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Updated: Jun 27, 2026

Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting
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Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting

Published on: December 9, 2022

Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling

Yuval Ben-Abu1, Yufeng Zhou, Noam Zilberberg

  • 1Department of Life Sciences and the Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel.

Nature Structural & Molecular Biology
|December 23, 2008
PubMed

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Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
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Electrical Synapses

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