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Updated: Aug 10, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
Characteristics of platelet concentrates, with particular reference to Autopheresis C Plateletcell: correlation
1North London Blood Transfusion Centre, Colindale, UK.
Abstract:
The quality of platelet concentrates (PC) collected by the Autopheresis C cell separator was assessed in two Regional Transfusion Centres taking part in a multicentre study. This study also enabled the assessment of a new simple, rapid test of platelet function and comparison with more established tests, such as aggregation to adenosine diphosphate, as a tool for the quality testing of PC. The new test, based upon the measurement of mean platelet volume using automated haematological cell analysers, is rapid and uses the same samples as those used to estimate the platelet and leucocyte content of the concentrates. The high correlation between this test and the other tests of platelet function used in the study suggests that it is an ideal tool in the quality testing of platelet concentrates.

