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Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...

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Related Experiment Video

Updated: Jun 27, 2026

Imaging Local Ca2+ Signals in Cultured Mammalian Cells
09:30

Imaging Local Ca2+ Signals in Cultured Mammalian Cells

Published on: March 3, 2015

Image analysis of calcium release dynamics.

Christina M Freisinger1, Douglas W Houston, Diane C Slusarski

  • 1Department of Biology, University of Iowa, Iowa City, USA.

Methods in Molecular Biology (Clifton, N.J.)
|December 23, 2008
PubMed
Summary

Calcium (Ca2+) dynamics control embryonic development by interacting with Wnt signaling. Distinct Ca2+ release patterns antagonize Wnt/beta-catenin and modulate cell movements, revealing crucial developmental signaling pathways.

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2026-06-19T13:26:26.374476+00:00

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Last Updated: Jun 27, 2026

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