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Updated: Jun 27, 2026

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
Published on: June 16, 2014
First solvation shell effects on ionic chemical reactions: new insights for supramolecular catalysis
1Departamento de Ciencias Exatas e da Terra, Universidade Federal de Sao Paulo, 09972-270 Diadema, SP, Brazil. pliego@unifesp.br
Abstract:
This article presents a detailed discussion on medium effect on ionic S(N)2 reactions. Ion pairing and the first solvation shell play the main role on reactivity. Ab initio calculations are used to show that a combination of apolar molecular cavity with polar hydroxyl groups can have catalytic effects on these reactions. The present results open an avenue of development for supramolecular catalysts able to control bimolecular ionic reactions. In particular, this new catalytic concept could be useful in nucleophilic fluorinations.
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