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Understanding medication non-adherence in bipolar disorders using a Necessity-Concerns Framework.

Jane Clatworthy¹, Richard Bowskill, Rhian Parham

¹Centre for Behavioural Medicine, School of Pharmacy, University of London, UK.

Journal of Affective Disorders

|December 23, 2008

Summary

Medication non-adherence in bipolar disorder is linked to doubts about treatment necessity and concerns about side effects. Addressing these beliefs is key for improving patient adherence to medication.

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Area of Science:

Psychiatry
Clinical Psychology
Pharmacology

Background:

Medication non-adherence significantly impacts patients with severe mental disorders, leading to adverse clinical outcomes and increased healthcare costs.
Bipolar disorder management is particularly challenged by adherence issues, necessitating a deeper understanding of patient perspectives.

Purpose of the Study:

To evaluate the Necessity-Concerns Framework's effectiveness in explaining patient attitudes and adherence to bipolar disorder medications.
To identify specific beliefs influencing medication adherence in individuals with bipolar disorder.

Main Methods:

A sample of 223 individuals with bipolar disorder completed validated questionnaires assessing medication beliefs and adherence.
Data were collected from participants recruited via a patient organization newsletter.

Main Results:

Thirty percent of participants reported low medication adherence.
Reduced adherence was significantly associated with greater doubts about the necessity of treatment and increased concerns regarding medication side effects.
These associations remained significant regardless of mood state or demographic factors.

Conclusions:

The Necessity-Concerns Framework provides a valuable model for understanding medication attitudes in bipolar disorder.
Future interventions aimed at improving adherence should focus on identifying and addressing patients' specific beliefs and concerns about their prescribed medications.