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Published on: March 28, 2025
Midterm change of descending aortic false lumen after repair of acute type I dissection
Kay-Hyun Park1, Cheong Lim, Jin Ho Choi
1Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Bundang, Korea. drkhpark@yahoo.co.kr
Background:
Persistent false lumen in the descending aorta after repair of acute type I dissection adversely affects long-term prognosis. In this study, we investigated changes of the descending aortic false lumen during the midterm postoperative period.
Methods:
Postoperative computed tomographic (CT) images of 122 patients who underwent conventional ascending with or without arch replacement for acute type I dissection were reviewed. Patency and width of false lumen and maximal diameter of the aorta were compared between early and last follow-up images. Changes were analyzed separately in the thoracic and abdominal segments.
Results:
In early CT, thoracic false lumen was patent in 85 patients (69.7%), and abdominal false lumen was patent in 111 patients (91.0%). Among these, the false lumen remained patent after a mean interval of 33.6 months in 69 patients (81.1%) and 105 patients (94.6%), respectively. In 58 patients (47.5%), the descending aorta dilated by 1 cm or more. Dilatation occurred more frequently in the thoracic aorta and in patients with patent or wide false lumens, larger aortic diameter, Marfan syndrome, younger age, and male sex. Meanwhile, shrinkage of thoracic false lumen occurred in 36 patients (29.5%). Such shrinkage occurred in 23 of 24 patients (95.8%) who had thrombosed and narrow false lumens in the thoracic aorta.
Conclusions:
Early postoperative characteristics of false lumen were helpful for predicting both dilation and regression. Our data show not only a high incidence of descending aortic dilatation after repair of acute type I dissection, but also shrinkage of thoracic false lumen in some patients. These findings can be used as control data for determining the benefit of more extensive or new surgical approaches.
Insights
Persistent false lumen in the descending aorta after acute type I dissection repair can lead to poor outcomes. This study found that early false lumen characteristics predict midterm changes, including significant descending aortic dilation in nearly half of patients.
Area of Science:
- Cardiovascular Surgery
- Thoracic Aortic Disease
- Medical Imaging
Background:
- Persistent false lumen in the descending aorta after acute type I dissection repair is linked to adverse long-term prognosis.
- Understanding midterm changes in the descending aortic false lumen is crucial for patient outcomes.
Purpose of the Study:
- To investigate the midterm changes of the descending aortic false lumen after surgical repair of acute type I dissection.
- To identify predictors of descending aortic dilation and false lumen regression.
Main Methods:
- Review of postoperative computed tomographic (CT) images from 122 patients who underwent repair for acute type I dissection.
- Comparison of early and last follow-up CT images to assess false lumen patency, width, and maximal aortic diameter.
- Analysis of changes in both thoracic and abdominal segments of the descending aorta.
Main Results:
- The descending aorta dilated by 1 cm or more in 47.5% of patients within a mean follow-up of 33.6 months.
- Dilatation was more common in the thoracic aorta and associated with patent/wide false lumens, larger aortic diameter, Marfan syndrome, younger age, and male sex.
- Thoracic false lumen shrinkage occurred in 29.5% of patients, particularly those with initially thrombosed and narrow false lumens.
Conclusions:
- Early postoperative false lumen characteristics are predictive of both midterm aortic dilation and regression.
- A significant proportion of patients experience descending aortic dilation after repair, but some also show false lumen shrinkage.
- These findings provide essential control data for evaluating novel surgical strategies for acute type I dissection.
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