Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nanozyme-Reinforced miR-197-3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

A "signal-on" electrochemical sensor for the rapid hyaluronidase activity detection in biologics and urine samples.

Analytica chimica acta·2026

Same author

Engineered Exosomal miR-146a-5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid-Induced Osteonecrosis of Femoral Head.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Development of an Indirect Competitive Chemiluminescent Enzyme Immunoassay for the Detection of 2,4-Dichlorophenoxybutyric Acid in Foods.

Luminescence : the journal of biological and chemical luminescence·2026

Same author

Eruptive xanthomas: a case report with literature review focusing on pathogenesis and clinical management.

Open life sciences·2026

Same author

Development of a High-Throughput Indirect Competitive Chemiluminescence Enzyme-Linked Immunoassay for the Rapid Detection of Bongkrekic Acid in Tremella Fungus and Rice Noodles.

Foods (Basel, Switzerland)·2026

Same journal

Oncogenic Viruses and Inhaled Microplastics: A Double Hit Hypothesis for Asthma Progression and Lung Cancer Development.

Reviews in medical virology·2026

Same journal

Dysregulated Metabolism in People Living With HIV in the Modern ART-Era: A Systematic Review of Targeted Metabolomics Studies.

Reviews in medical virology·2026

Same journal

From Norovirus to Andes Hantavirus: Indirect Viral Transmission and Emerging Prevention Strategies for Cruise Ship and Confined Environments.

Reviews in medical virology·2026

Same journal

Matrix Metalloproteinases and Viral Hepatitis: A Complex Interplay Driving Liver Fibrosis, Immune Dysregulation, and Hepatocarcinogenesis.

Reviews in medical virology·2026

Same journal

Kyasanur Forest Disease: Advances in Experimental Animal Models, Immune Assays, and Challenges in Vaccine Development.

Reviews in medical virology·2026

Same journal

A Cross-Country Evaluation of Respiratory Syncytial Virus and Human Metapneumovirus Surveillance Systems: Identifying Gaps and Best Practices for Improved Disease Monitoring.

Reviews in medical virology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 13, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Published on: March 24, 2017

An introduction to epitope prediction methods and software.

Xingdong Yang¹, Xinglong Yu

¹Department of Veterinary Medicine, Hunan Agricultural University, Changsha, Hunan, P. R. China.

Reviews in Medical Virology

|December 23, 2008

Summary

This summary is machine-generated.

This review summarizes T- and B-cell epitope prediction tools and databases, offering guidance for researchers. It aims to familiarize biomedical scientists with these essential bioinformatics resources.

More Related Videos

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

A Protocol for Computer-Based Protein Structure and Function Prediction

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Related Experiment Videos

Last Updated: Jan 13, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Published on: March 24, 2017

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

A Protocol for Computer-Based Protein Structure and Function Prediction

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

Area of Science:

Immunoinformatics
Computational Biology
Bioinformatics

Background:

Epitope prediction is crucial for vaccine design and immunology research.
Numerous computational tools and databases exist for identifying T-cell and B-cell epitopes.
Researchers, especially those new to the field, require guidance on selecting and utilizing these resources effectively.

Purpose of the Study:

To review current prediction methods and algorithms for T-cell and B-cell epitopes.
To provide a comprehensive summary of available online epitope prediction software and databases.
To guide clinical and basic biomedical researchers in effectively using these bioinformatics tools and databases.

Main Methods:

Literature review of existing epitope prediction methods and algorithms.
Compilation and summary of currently available online software and databases for epitope prediction.
Development of guidance for effective utilization of these resources.

Main Results:

A comprehensive overview of T- and B-cell epitope prediction methodologies.
A curated list and description of online epitope prediction tools and databases.
Insights and directions for future research in epitope prediction.

Conclusions:

This review offers valuable direction and insights for researchers in immunoinformatics.
It serves as an effective guide for biomedical researchers unfamiliar with epitope prediction tools.
Facilitates better utilization of online bioinformatics resources for immunological studies.