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Related Concept Videos

Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
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Traits and States01:17

Traits and States

Personality traits represent consistent patterns in behavior, thoughts, and emotions, reflecting an individual's tendencies across various situations. For example, extraversion, a well-known trait, manifests in individuals as talkative, energetic, and enthusiastic behaviors. These traits are stable over time, offering a reliable framework for predicting how people might act in different contexts. However, they do not define every moment of an individual's life. In contrast to traits, states are...

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Updated: Jun 26, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

Vasovagal syncope: state or trait?

Anna Serletis Bizios1, Robert S Sheldon

  • 1Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.

Current Opinion in Cardiology
|December 24, 2008
PubMed
Summary
This summary is machine-generated.

Vasovagal syncope may have a genetic origin, supported by family studies and specific traits. This review explores the evidence for a genetic basis of vasovagal syncope.

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Area of Science:

  • Genetics
  • Cardiology
  • Epidemiology

Background:

  • Vasovagal syncope lacks a comprehensive etiological theory.
  • Several characteristics suggest a potential genetic component.

Purpose of the Study:

  • To present the rationale for investigating a genetic origin of vasovagal syncope.
  • To critically review recent findings on the genetic basis of this condition.

Main Methods:

  • Review of existing literature and epidemiological data.
  • Analysis of familial aggregation and inheritance patterns.
  • Examination of candidate gene studies.

Main Results:

  • Vasovagal syncope exhibits incomplete population effect, persistent phenotype, and lack of clear infectious/autoimmune causes.
  • Familial studies suggest autosomal dominant transmission with incomplete and sex-specific penetrance.
  • Early candidate gene research implicates sympathetic signal transduction pathways.

Conclusions:

  • Epidemiological features strongly indicate a possible genetic origin for vasovagal syncope.
  • Further genetic research is warranted to elucidate the underlying mechanisms.