[Evaluation of drug therapy in epilepsy]

Supposing that in evaluation of therapeutical efficacy of the definite antiepileptics the most important is its clinical effect, the aim the study was to analyse retrospectively correlation of clinical effects, EEG characteristics and serum carbamazepine concentration in a group of patients with subtherapeutical and in a group with therapeutical antiepileptic concentrations. The results of the study have shown no positive direct correlation among clinical effects, EEG characteristics and serum drug concentrations. It has been concluded that in evaluation of therapeutical carbamazepine efficacy of the essential importance is its clinical effects.